An Echo in the Bone is the seventh book in Diana Gabaldon's Outlander series, continuing the story of Jamie and Claire Fraser during the American Revolution, while also following their daughter Brianna, her husband Roger, and Jamie's illegitimate son William in separate storylines. The plot intertwines their lives as they navigate the war, with Jamie and Claire facing conflict with William, and Brianna and Roger dealing with life in the 20th century after returning from the past.